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Symbol
Name
ID
Dnmt3a
DNA methyltransferase 3A
MGI:1261827
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Acute myeloid leukemia
Myeloid leukemia
Lymphoma
Myelodysplasia
Disease(s) Associated with DNMT3A
acute lymphoblastic leukemia
acute myeloid leukemia
myelodysplastic syndrome
Tatton-Brown-Rahman syndrome

Mouse Phenotypes
increased common myeloid progenitor cell number
abnormal bone marrow hematopoietic cell morphology
increased hematopoietic stem cell number
Availability Mouse Genotype
Dnmt3atm1Trow/Dnmt3a+
Tg(Mx1-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory